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Alternatives Assessment - method for comparing chemicals/materials with focus on toxicity

Name of service (page headline, shown in promos – maximum of 70 characters incl. spaces): Comparing chemicals and materials - with focus on toxicity Lead (include SEO-words and the main benefits for your target groups. Stick to one paragraph, maximum 2-3 sentences):

As an organization, it can be difficult to know whether you are making better or worse choices in the green transition. What is a more sustainable alternative? We can help you by categorizing chemicals and materials based on their impact on the sustainability goal: non-toxic environment.

Purpose/Benefit:

Avoid the pitfalls of choosing hazardous alternatives

There are several reforms underway within the EU's Green Deal to speed up a fair transition to a climate-neutral, circular economy whilte protecting biodiversity and reach a non-toxic environment. Part of the transition means that we need to look for alternative ways to produce and manufacture chemicals, materials, and goods - but how do we know if we are choosing genuinely better alternatives?

How can we help you?

We can help you by obtaining data and categorizing the hazard of chemicals from "Avoid" to "Safer". We use the EU's criteria for safe and sustainable design, which are under development within the EU's chemicals strategy for sustainability (2020). You can use the data and guidance to understand trade offs and risks for alternatives - before it's too late. Our method for chemical safety can be combined with life cycle analysis to also understand climate impact of different choices.

Method (what/which methods are used to perform the service):

Alternatives assessment - A method for scientifically comparing alternatives

We use the Alternatives Assessment method developed to manage "regrettable substitution". Regrettable substitution means choosing an alternative which is as hazardous as the chemical/material you want to replace. A well-known example is bisphenol A, a common plastic chemical with endocrine-disrupting properties. 

The most common substitute for Bisphenol A is Bisphenol S. A chemical that can also cause endocrine disruption. Another example of regrettable substitution is when a substitution transfers the risk to another part of the life cycle. For example a chemical is substituted to protect consumers, but introduces an unacceptable risk for occuptiontal health instead. To avoid this risk, we assess alternatives for many health hazards.

How do we compare chemicals?

We use criteria from the EU's current version of the "Safe and sustainable by design" framework" (SSbD) (2022). The method involves collecting information on legislation, hazard classifications according to CLP and voluntary Substitution Lists. We also make sure to check for data gaps on hazard. Lack of data can give a first impression that an alternative is safe. But no data does not mean an alternative is safe, just that it needs more testing. 

We can adapt the assessment depending on your need and budget. We suggest that we start by screening each chemical for legislation, two voluntary restriction lists and approximately 20 hazard classifications. 

Extend the sustainability scope

Do you want to include other important aspects for your green transition? Alternatives assessment is a method to compare and choose safer alternatives while including function, climate, and economy. We have colleagues that know life cycle analysis, materials, technoeconomy, circular economy, etc. We can involve them in the assessment and tailor it to your needs.

Delivery (what does the client get after performed service – e.g. a report, certificate etc.):

The basis for making informed decisions

You will receive a summary in an Excel sheet based on the agreement. Listed below are examples of what type of information the summary can contain. The delivery comes with a walk-through of the documentation and guidance going forward. We can also prepare presentation material if necessary.

The chemical with associated CAS number is categorized according to the EU's SSbD criteria (2022 v.1):

  • Cut-off criteria: Most harmful substance, corresponds to Particularly hazardous substances (SVHC). These substances cannot be considered safe and should be phased out as much as possible.
  • Safety level 1: Substances of concern, substances with serious properties that should be replaced by safer alternatives.
  • Safety level 2: Other hazard classes, substances with "less potent" hazard classifications. The risk can be managed through exposure. 
  • Safety level 3: Safer alternatives

Examples of legislation or restricted lists:

  • EU REACH regulation
  • POPs Regulation
  • Chemsec SIN list
  • The Swedish Chemicals Agency's PRIO - a tool for substitution

Data gap

  • Flag if the substance is not registered according to REACH
  • Flag if REACH dossier lacks important data for cut-off criteria/most harmful substances and may be a regrettable substitute.
  • Opportunities to follow-up with data modeling to fill data gaps.
  • Opportunities to follow-up with in-depth literature study.
  • Opportunities to follow-up with toxicity tests. 
Area:
Wind power
Additive manufacturing
Work environment
Batteries
Bioeconomy
Fire safety
Biorefinery
Cement and concrete
Circular transition
Design
Electromobility
Electronics
Formulated products
Packaging
Infrastructure
Chemical processes and products
Corrosion
Life cycle analysis
Lightweight solutions
Maritime
Pulp and paper
Material transition
Plastics
Product safety
Built environment
Textile
Wood technology
Healthcare and social care
Surface technology
Contact person (Enter one name per field. Activated personal contact pages will appear automatically): Nina Melander, Forskare
Alternatives Assessments
Field measurements: No Price type: 1 Division: Division Materials and Industry Preparation: Description of preparation Preparation information:
  • For chemicals, we need identification names or numbers such as CAS number, EC number, InChi, SMILES, etc.
  • Associated Chemical Safety Data Sheets (SDS) if available.
  • For materials: A composition list with information on chemical content including identification names or numbers. 
Certification and marking: Not applicable Type of service:
Innovation services
Testing / Analysis / Evaluation
Available from remote
Instrument: Not applicable General area: Not applicable Order information: Please, contact the person listed below for more information or ordering. Divison (OLD): Division Materials and Industry Delivery level: Non-accredited
nina.melander@ri.se
/en/node/9710
3. Good health and well-being
6. Clean water and sanitation
9. Industry, innovation and infrastructure
12. Responsible consumption and production
14. Life below water
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Chemical and biological analysis Sekundär områdes navigation:
Circular transition
Health and life science
Tjänstetyp tagg: Konsultuppdrag

New substance offers hope for a cure against multi-resistant bacteria

Drug development

The Swiss biotech company Juvabis is developing a new substance, EBL-1003, as part of the ENABLE project. The substance could be used to treat patients with illnesses caused by multi-resistant bacteria.

Antibiotic resistance is rising to dangerously high levels in all parts of the world. New resistance mechanisms are emerging and spreading globally, threatening our ability to treat common infectious diseases. A growing list of infections – such as pneumonia, tuberculosis, blood poisoning, gonorrhea, and foodborne diseases – are becoming harder, and sometimes impossible, to treat as antibiotics become less effective.

The EBL-1003 substance could, in the future, potentially be used to treat critically ill patients in hospital settings. EBL-1003 is a crystalline free base of an aminoglycoside designed to treat Gram-negative bacterial infections. EBL-1003 for infusion has demonstrated potent broad-spectrum activity and rapid bactericidal killing of Acinetobacter baumannii and other Gram-negative bacteria, including organisms identified by the World Health Organization (WHO) and the Centers for Disease Control and Prevention as urgent and serious threats to human health.

"EBL-1003 has the potential to replace aminoglycosides currently used in the clinic, but whose utility is seriously threatened by rising antibiotic resistance", says Sven Hobbie, CEO at Juvabis. "We were able to make significant progress in the development of a new treatment thanks to our collaboration with RISE".

We were able to make significant progress in the development of a new treatment thanks to our collaboration with RISE

Test are showing positive results

The molecule that the injectable substance is based on is already in use in veterinary treatment, primarily outside of Europe and the United States. During phase 1, Juvabis collaborated with RISE to further develop the drug, which was subsequently tested on healthy volunteers with positive results.

"During this initial phase, we bought the original substance from the manufacturer and analyzed and refined it in our laboratory in Södertälje", says Bo Lassen, RISE's project manager who is also in charge of the formulation aspect of the project. "We've designed analytical methods and formulations, improved the solid state of the molecule to make it more stable for storage, and evaluated its toxicity and tolerability among other things".

EBL-1003 underwent phase 1 clinical trials as part of the European Gram-Negative Anti-Bacterial Engine (ENABLE), a project sponsored by the Innovative Medicines Initiative that completed in 2021, with another clinical trial sponsored by the National Institutes of Health currently in preparation.

More thorough research is now being conducted to advance the substance's development into a treatment that can be used in healthcare. Even though ENABLE ceased last year, Juvabis’s partnership with RISE continues, and a new funding application has been submitted to also develop the compound for inhalation.

Nicolaas Schipper

Head of manufacture
+46 70 217 78 20 Read more about Nicolaas
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Drug development Sekundär områdes navigation:
Biotechnology
Chemical and biological analysis
Chemical products and processes

New drinking water directive for increased resilience and sustainability

Drinking water

For a resilient water supply, both the supply and quality of the water need to be ensured. It demands materials that last over time and do not cause contamination. The latest update to the EU Drinking Water Directive brings new requirements affecting everyone involved in water supplies, from municipalities and property owners to producers of materials and products. The Materials in contact with drinking water network, operated by RISE, follows how the directive is implemented in Swedish law and provides support and guidance.

The EU Drinking Water Directive has been developed to create a similar management of water in the Member States. The aim is to take care of our water resources so that future generations will have access to a sufficient supply of good quality water. The latest update to the directive came into force in January 2021, with many new items that affect everyone who works with water supply.

“The aim is to better cover the entire chain, from source to tap, and include materials that come into contact with drinking water as well as building aspects that have not been regulated in the Drinking Water Directive before”, says Mylène Trublet, research and business developer at RISE and project manager of the Materials in contact with drinking water network.

Increased requirements for materials in contact with drinking water

The requirements for materials coming into contact with drinking water are governed by Article 11 of the Drinking Water Directive and apply both to new installations and repairs to existing installations for the outlet, preparation, storage and distribution of drinking water.

The changing requirements on materials, type-approval and testing are some of the key issues facing the members of the RISE network Materials in contact with drinking water. Members include the water suppliers as well as manufacturers of materials and products. This network gives access to the latest research and good examples in the field; members meet at seminars and can exchange experiences with each others. How the new directive is implemented in Swedish law is a very current issue.

“The network follows the work on the Drinking Water Directive, at EU and national level. At our next seminar, Boverket, the National Board of Building, Housing and Planning, will provide information about the process for the implementation of the directive into Swedish law, RISE and KIWA will talk about the approval process”, says Mylène Trublet.

The seminar "Materials and products in contact with drinking water" is being held 27 September 2022, and is open to all interested parties.

Tougher requirements could drive the development of unleaded brass

An example of a branch being affected by the tougher requirements is brass industry who have lead in their raw materials. In the new directive, the limit value for lead in drinking water has been halved. In addition, there is an ongoing discussion about the inclusion of lead on the authorisation list in Reach.

“In the long term, there may be a total ban of lead in materials coming into contact with drinking water. If the brass industry wants to live in the future, it will have to reposition, even if it is a challenge, says Mylène Trublet.

Lead makes brass easier to process and is used in valves, water meters and other components. RISE has participated in several research projects looking at both the possibility of manufacturing brass with a lower lead content and to making completely lead-free brass.

Studying how materials, such as lead-free brass, behave in contact with different types of water, can be done in new RISE test environment in Kista called the Water Rig.

“Here, we can compare different materials and products in different types of water and see how they behave, how they degrade and whether substances leach from the material. In the Water Rig, we can also study biofilms and we can test new sensors,” explains Mylène Trublet.

Products with longer lifespan

There are not only increased requirements in the new Drinking Water Directive, it also includes an easing that will be appreciated by many manufacturers.

“The type-approval process for materials and products in contact with drinking water will be harmonised at a certain level for all countries in the EU, with the Directive setting minimum requirements. I see that as positive, although some countries may have additional requirements”, says Mylène Trublet.
In addition to the requirements of the Directive, Sweden aims to develop materials and products for drinking water and wastewater that have a lifespan of 100-150 years.

“The goal is ambitious but it will also contribute to resilience and preparedness. If we can rely on our management system being robust and sustainable, we will have less unplanned maintenance and better readiness in the renovation and renewal of management systems. It is a good idea and also essential that in Sweden, we work towards sustainability and product durability – that is also what we at RISE are working on”, concludes Mylène Trublet.

Materials in contact with drinking water network

This network has 30 members and brings together principals, trade associations, manufacturers of materials and products and relevant authorities.

Members gain access to up-to-date information on legislation, regulatory framework, research, and materials and product development. The network meets regularly to discuss common issues and needs in the field.

Read more about the Materials in contact with drinking water network

Charlotta Obitz

Marknadschef
+46 73 088 76 75 Read more about Charlotta
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Sustainability: 6. Clean water and sanitation Water Sekundär områdes navigation:
Climate adaptation
Chemical and biological analysis
Materials and durability

Non-toxic from the start through AI analysis of patent data

Plastic bottles

Could a pilot study on European patent data be the first step to preventing a future chemical disaster? Researchers at RISE have built a machine learning model that identifies bisphenols and, potentially, other hazardous chemical substances. With further training and development, the social benefits can be enormous.

The world’s chemical inspectorates are essentially always one step behind. Bisphenols are a telling example. First comes the suspicion: is the substance an endocrine disruptor? Then the evidence: yes, it is. And then the regulation: EU-wide ban on bisphenol A in baby bottles in 2011, and then in thermal paper (used for receipts) in 2020.

The problem? Regulations are introduced after the damage has already been done, while new variants frequently appear that have not yet been regulated, forcing authorities to constantly play catch up.

There is undoubtedly a great need for a powerful and proactive way of working. In collaboration with the Swedish Chemicals Agency and the Swedish Patent and Registration Office, Researchers at RISE have used data from the European Patent Office to evaluate a number of AI methods.

“Patent data is unusually well-organised,” says Olof Görnerup, researcher in machine learning and large-scale data analysis at RISE. “It is structured to be machine-readable and easy to process.”

Furthermore, researchers state that patent data is a good way to understand what is happening in technology development. Granted patents normally precede broad implementation by several years and contain information about the chemical substances in a product. Authorities can therefore learn early on whether problematic chemicals will be introduced to the market.

Language technology presents new possibilities

In the past, this type of mapping has been carried out over months of manual keyword searches. Work that is also difficult to verify – how does one know that all relevant documents have been included?

The rapid development of language technology presents brand-new possibilities.

“Instead, we used semantic search through an AI model that ‘understands’ more of the text,” explains Görnerup. “That certain words and phrases relate to a subject. It involves finding words and phrases that are semantically similar to each other.”

It’s important to understand where chemicals are used

To determine which documents are relevant, the AI system had first been trained on reference data from a previous mapping of bisphenol-related patents and the PubChems database. A small selection of documents with known classifications were shown to an AI-model, which then utilised this information to find other relevant documents.

High precision with AI

The results showed that the best-faring AI method was able to identify 96 percent of all relevant patents (precision). While 91 percent of the patents identified as relevant were in fact relevant (recall).

“We immediately saw that there is massive potential to use AI in this area,” says Görnerup.

The researchers stress that more development is needed and the models need to be fine-trained. Among other things, there is a lot of image data in the form of line drawings and technical diagrams that the pre-trained models (including CLIP) had difficulty processing. And much of the chemical information in patents is image form, so there is great potential for better searching using computer vision.

According to the researchers, something within close reach is the creation of a tool for the Swedish Chemicals Agency to automatically scan for hazardous chemicals without requiring extensive insight into various technology fields:

“It’s important to understand where chemicals are used. A hazardous chemical that is only used in controlled processes does not pose as much of a risk as a chemical that may be less hazardous but which is at risk of spreading widely.

“Are there niche fields of technology where such use slips under the radar? For example, thermal paper was discovered quite late. It is used everywhere; many people handle it daily in receipt printing.

“Imagine the benefits that could be achieved if another PFAS disaster could be avoided.”

Olof Görnerup

Senior Researcher
+46 70 252 10 62 Read more about Olof
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Sustainability: 12. Responsible consumption and production Chemical and biological analysis Sekundär områdes navigation:
Artificial intelligence
Data Science
Risk and security

Gas measurements Dilute - Non-Condensable Gases, DNCG

Gas measurements - DNCG
TRS

What is normally called dilute non-condensable gases, DNCG contains a mixture of different sulphur-containing substances; hydrogen sulphide, methyl mercaptan, DMS and DMDS.

Portable gas chromatograph.

The need to collect and destroy so‑called particulate matter (DNCG) has increased as the EU has tightened requirements for industry to use the best available technology to reduce sulphur emissions to air.

Some common sources of gas emissions in industrial processes include:

Combustion:
The combustion of fuels such as coal, oil or natural gas can result in emissions of carbon dioxide (CO₂), nitrogen oxides (NOₓ), sulphur dioxide (SO₂) and other pollutants, depending on the combustion process and the quality of the fuel.

Industrial processes:
Many industrial processes generate gases as by‑products of chemical reactions or material handling. These may include greenhouse gases such as methane (CH₄), as well as industrial pollutants such as ammonia (NH₃) and hydrogen cyanide (HCN).

Waste management:
Emissions from waste treatment, including landfill sites and wastewater treatment plants, may include landfill gases such as methane and carbon dioxide, as well as other hazardous chemicals released during the decomposition of organic material.

DNCG – Total Reduced Sulphur Amount:

The total of the reduced sulphurous odorous compounds formed during pulp production: hydrogen sulphide, methyl mercaptan, dimethyl sulphide and dimethyl disulphide, expressed as sulphur.

Diluted non‑condensable odorous gases: 

Gases containing DNCG that are not strongly odorous (e.g., gases from tanks, washing filters, chip bins, lime mud filters or dryers).

Measuring weak gases at mills

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Analyses of gases in ventes from tanks and from landfill gas

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Lars Sundvall

Forskare
+46 70 526 52 21 Read more about Lars
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Division (OLD): Division Bioeconomy Division: Division Bioeconomy Chemical and biological analysis

Chemical analysis – biomass to product

Chemical analysis – biomass
Låga

In the cellulose industry, it is important that process chemicals are carefully analysed, monitored and classified to ensure correct handling and any required post‑processing of the material.

Cellulose is a key raw material in biobased products, which places high demands on ensuring that process chemicals do not leave harmful residues. Contaminants that may arise during bleaching, cooking and dewatering therefore need to be systematically monitored.

Targeted analyses of chemical residues, pH levels and chlorine-related contaminants provide a basis for ensuring product quality and sustainability. Common sample types include lime, process liquids, soap, tall oil, backwater and methanol. Dedicated analysis packages are also available to assess risks related to scaling and inkrustation.

Thorough monitoring supports safer and more circular cellulose-based products with minimised levels of unwanted substances.

Wood and pulp

Our analyses cover fibre content, residual alkali, sulphur compounds such as sulphide, sulphite, sulphate and thiosulphate, total sulphur, oxalate, chloride, metals, and carbohydrates in both polymeric and monomeric form. We also analyse lignin and its molecular weight distribution, levels of tall oil and terpenes, hydroxy and volatile acids, as well as total solids and ash content.

Metal analysis

Metal analyses include, among others, calcium, copper, iron, magnesium, manganese, potassium, sodium, cadmium and lead. For broader and more sensitive multi‑element analyses, ICP‑OES is used, enabling simultaneous quantification of multiple elements in process liquids, solid samples, extracts and ash. Common target elements include aluminium, barium, cobalt, chromium, phosphorus, silicon and zinc.

Gas analysis

Gas analyses include, among others, hydrogen sulphide (H₂S), carbon dioxide (CO₂), sulphur dioxide (SO₂), as well as other volatile inorganic and organic compounds. These analyses support emissions monitoring, process control and compliance with environmental requirements.

Inorganic compounds

Inorganic compounds are analysed using high‑sensitivity instruments to identify salts, metals, oxides and anions, even at very low concentrations. We offer both qualitative analyses for identification and quantitative analyses for concentration determination. Techniques such as GC‑MS, HPLC, ICP‑MS and FTIR enable detection down to ppm and ppb levels, which is essential for trace analysis and control of residual substances.

Process liquids

Process liquids in the cellulose industry are analysed with respect to factors that affect process stability and final product quality. This includes anion concentrations and cation demand, carboxyl and uronic acids, total ASA content, carbohydrates, lignin and optical brighteners. Backwater is analysed for the same parameters, as well as starch.

Black liquor

Black liquor from the kraft pulping process contains both organic and inorganic components that need to be analysed to optimise chemical recovery, energy yield and process balance. Key parameters include fibre content, residual alkali, sulphur compounds, total sulphur, oxalate, chlorides, metals, carbohydrates, lignin including molecular weight distribution, tall oil, terpenes, hydroxy and volatile acids, as well as total solids and ash content.

White liquor and green liquor

White and green liquors are analysed to ensure a stable and efficient chemical balance in the recovery system. Important parameters include alkali content (total, active and effective), carbonates, sulphur components such as sulphide, sulphite, sulphate and thiosulphate, total sulphur, potassium and sodium, chlorides and metal concentrations.

Lime

Lime is analysed for free lime content, acid‑soluble sodium and metal concentrations. Common analysis parameters include sodium, magnesium, calcium, manganese, iron, aluminium, silicon, phosphorus and sulphur.

Tall oil

Tall oil is assessed based on acid value, content of neutral substances, fatty acids and resin acids, water and ash content, as well as total sulphur and sodium content. Soap is analysed with respect to theoretical tall oil yield, alkali content, calcium content, dry solids and calorific value.

Methanol

Methanol and contaminated condensate are analysed for methanol, water, ammonium, total nitrogen, TRS components such as hydrogen sulphide, methyl mercaptan, dimethyl sulphide and dimethyl disulphide, as well as total sulphur. Terpenoids, including α‑pinene, β‑pinene, 3‑carene and limonene, as well as mono‑, sesqui‑ and diterpenoids, are also analysed.

GC‑MS screening is used to identify volatile compounds that affect odour, product quality and environmental impact.

Organic substances

Organic acids

Organic acids and related compounds are analysed to assess the degree of degradation and overall process quality. Common analytes include levulinic acid, ethanol, glycerol, lactic acid, formic acid and acetic acid. The furan derivatives HMF and furfural are used as indicators of carbohydrate degradation and can also be quantified in black liquor to evaluate cooking conditions.

Organic compounds

Organic compounds and extractives are analysed in forest raw materials, process liquids and by‑products. The analyses include, among others, lignans, fatty acids and resin acids, sterols, steryl esters, triglycerides, as well as process chemicals such as anthraquinone. Rosin is analysed with respect to its impact on sizing performance and odour. Other carbon‑ and sulphur‑containing compounds, such as methanols, aldehydes, thiophenes and disulphides, are also analysed, as they are important for both process control and environmental assessment.

Scaling risk

High concentrations of extractives can increase the risk of precipitation, leading to operational disturbances and increased maintenance requirements. It is therefore important to analyse key parameters such as carbonate, sulphate, oxalate, calcium, sodium, aluminium, silicon and total solids. The results are used to optimise the process and prevent scaling‑related problems.

Microanalysis of particles and deposits

Using SEM‑EDS, we analyse solid particles, deposits and spots to determine their chemical composition and origin. The analyses provide a basis for identifying the causes of deposits, assessing risks and proposing measures that contribute to a more stable and robust process.

Textile

Viscosity measurements are used to assess molecular weight and degree of degradation in cellulose‑based textiles, particularly in recycling applications. Fibre analysis using light microscopy provides information on fibre type and fibre dimensions, while scanning electron microscopy (SEM) is used to study morphology and identify potential defects.

Metal concentrations are determined using ICP‑OES or ICP‑MS. Common analysis parameters include copper, zinc, chromium, lead, nickel, cadmium, iron, aluminium, sodium and potassium. Metal analyses are important for assessing environmental and health aspects as well as the material’s suitability for recycling.

Christina Wedin

Coordinator
+46 10 722 32 47 Read more about Christina
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Attach documents:

Analysis Pulp and Paper (pdf, 249.03 KB)


Analysis enquiry (pdf, 302.15 KB)

More information:

If you have any questions, please contact us:

Chemical analyses: lab.ka@ri.se 

Gas chromatography, identification of chemical components: lab.gc@ri.se

Problem solving, identification of unknown substances, etc.: lab.ts@ri.se

 

Form for analysis requests and orders: 

Division (OLD): Division Bioeconomy Division: Division Bioeconomy Chemical and biological analysis

Problem solving in processes and products

Problem solving in processes and product
Eucalyptus

Problem solving in processes and products involves analysing organic and inorganic compounds, surfaces, elements. FT-IR, light microscopy and SEM / EDX are most common but also GC-MS, separation techniques are also used to solve the problems that processes and products encounter.

Problem solving in processes and products is the process of identifying, analysing, and resolving issues or faults in a system, product, or process. It involves systematically examining possible causes of a problem to find and implement a solution.

Problem solving is essential when processes and products become contaminated for various reasons, causing operational issues that can lead to economic and environmental consequences, as well as potential customer complaints.

Microscopes

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Scanning Electron Microscopy (SEM)

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Organic and inorganic compounds

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Identification of materials

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Chemical compound separation

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Analyse inorganic and organisc ions

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Metal analysis

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Jessica Sjöstedt

Forsknings- och utvecklingsingenjör
+46 10 722 32 38 Read more about Jessica
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Christina Wedin

Coordinator
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More information:

Pulp, Paper, and Materials:

You can analyse a wide range of samples, including scrapes, dots, oils, solutions, and more, without the need for sample preparation. Our analysis is both qualitative and quantitative, providing valuable insights for problem-solving, addressing customer complaints, and supporting quality control across different raw materials.

Types of samples for troubleshooting:

  • Pulp, paper, cardboard
  • Scrapes, dots, rubber cloth
  • Printed end products, solutions, oils, smears
  • Incubators, piglets

Identification of organic and inorganic compounds: 

  • Organic compounds: Polymers, biomolecules (lignins, carbohydrates, oligosaccharides, polysaccharides, cellulose, vitamins), aromatic compounds, aliphatic compounds, hydrocarbons.
  • Molecular groups: Alkanes, alkenes, arenes, alkynes, esters, carboxylic acids, alcohols.
  • Inorganic compounds: Carbonates, carbides, organometallic complexes, minerals, halides, sulphates.

Materials: Our troubleshooting capabilities extend to a variety of materials, including:

  • Scrapes, dots, rubber cloth, printed end products, incrustations, metals.

Important considerations for sample submission:

  • Ensure scrapes are placed in a jar when sampling.
  • Avoid marking too close to the defect or problem area.
  • Exposure tests are carried out at RISE in Örnsköldsvik.
  • Send reference samples for comparison, including process and functional chemicals/materials. A good reference helps compare the problem sample with a controlled or ideal sample.
Division (OLD): Division Bioeconomy Division: Division Bioeconomy Chemical and biological analysis

Analysis of siloxanes (D4, D5, D6) in textile and plastics

Name of service (page headline, shown in promos – maximum of 70 characters incl. spaces): Analysis of siloxanes (D4, D5, D6) in textile and plastics Lead (include SEO-words and the main benefits for your target groups. Stick to one paragraph, maximum 2-3 sentences):

It is important that the materials on the market are free of hazardous and regulated substances. Chemical analysis is a way to gain control over the products' chemical content.

Purpose/Benefit:

Society and consumers place great demands on companies and their products. The legislation also means that you as an actor must have complete information and control over which chemicals your products contain. It is especially important with products for children and goods that come into contact with the skin, such as clothes and accessories.

We help you interpret chemical legal requirements and restrictions that apply to goods made of textile materials and plastics and that are linked to, for example, REACH and POPs. We suggest which analyzes you need to do based on legal requirements, but also other requirements specifications such as eco-labels or procurement requirements.

Method (what/which methods are used to perform the service):

Determination of siloxanes D4, D5 och D6 (SVHC substances) in silicone, plastics and textile.

QUANTIFICATION OF RESIDUAL AMOUNTS OF CYCLIC VOLATILE METHYL SILOXANES IN SILICONE ELASTOMERS described by CES – Silicones Europé, revised version January 2019

Sample amount 20 grams

Delivery (what does the client get after performed service – e.g. a report, certificate etc.):

Written report in Swedish or English.

Delivery time:

The normal delivery time is 10 working days after ordering and received sample material.

Area: Chemical and biological analysis Contact person (Enter one name per field. Activated personal contact pages will appear automatically):
Carina Berglund, Forskare
Elisabeth Olsson, Forsknings- och utvecklingsingenjör
Pipetting of liquid in to a GC-vial for analysis
Field measurements: No Price type: 1 Division: Division Materials and Industry Preparation: No preparation required Standards:

Determination of siloxanes D4, D5 and D6 (SVHC substances)

QUANTIFICATION OF RESIDUAL AMOUNTS OF CYCLIC VOLATILE METHYL SILOXANES IN SILICONE ELASTOMERS described by CES – Silicones Europé, revised version January 2019

Certification and marking: Not applicable Type of service: Testing / Analysis / Evaluation Instrument: Not applicable General area: Not applicable Order information: Please order via the contact person(s) listed at the bottom of the page. Divison (OLD): Division Materials and Industry Delivery level: Not applicable
carina.berglund@ri.se,elisabeth.olsson@ri.se
/en/about-rise/operations/mission-governance/policy-documents/privacy-policy
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Chemical and biological analysis Sekundär områdes navigation:
Metrology
Plastics
Textiles
Health and life science
Tjänstetyp tagg: Provning

Analysis of colophony in products with skin contact

Name of service (page headline, shown in promos – maximum of 70 characters incl. spaces): Analysis of colophony in products with skin contact Lead (include SEO-words and the main benefits for your target groups. Stick to one paragraph, maximum 2-3 sentences):

Colophony, also referred to as rosin, is a term used to describe a collection of resin acids that are naturally present in the extractives of pine, spruce, and larch trees. Given that pine oil is a common byproduct of the wood distillation process, colophony is often found in significant quantities in pine oil.

Purpose/Benefit:

It is acknowledged that traces of colophony may be present in pulp and, consequently, may be found in various products. However, it is generally accepted that this does not usually cause any problems. However, a Danish study of 2,000 eczema patients found that 3.7% had an allergy from skin contact with colophony. The greatest risk of exposure to these substances is associated with prolonged contact, typically occurring in cases of adhesives utilised in plasters, bandages, cosmetic products, and sanitary items. This allergy has the potential to persist throughout a person's lifetime.

In the context of regulatory frameworks pertaining to hygiene and cosmetic products, there has been an observed increase in the demand for analysis in order to ascertain colophony levels. At RISE, we specialise in the measurement of colophony content, with the objective of ensuring compliance with safety standards and minimising the risk of allergic reactions.

Colophony is a naturally occurring substance that is found in a variety of products, including cosmetics, adhesives, paints, soaps, and industrial chemicals. It is sometimes referred to by different names, such as rosin, resin oil, and tall oil resin. It is imperative to be cognizant of these synonyms to ensure precise identification and analysis.

Method (what/which methods are used to perform the service):

The analysis of colophony levels in mass is achieved through the utilisation of gas chromatography for the purpose of examining resin acids. In certain instances, three particular resin acids – abietic acid, dehydroabietic acid, and 7-oxodehydroabietic acid – are employed as markers for colophony. In order to conduct this analysis, a minimum of 20 grams of mass is required.

Delivery (what does the client get after performed service – e.g. a report, certificate etc.):

RISE is responsible for the production of a report, the content of which is presented in Excel format, together with relevant images and diagrams. The data has been compiled in accordance with recognised methods, incorporating a measurement uncertainty assessment to ensure the reliability of the results. The report encompasses all pertinent parameters, accompanied by comprehensive comments and elucidations to facilitate enhanced comprehension.

Delivery time:

The delivery of results is contingent upon the order backlog and the scope of the assignment. The company's operational framework is designed to ensure the timely delivery of projects in accordance with the specific requirements of each client.

Express delivery is available at an additional cost for those requiring faster results. Should you wish to make an enquiry regarding prices and availability, please do not hesitate to contact us.

Area:
Work environment
Bioeconomy
Biorefinery
Chemical and biological analysis
Pulp and paper
Material transition
Plastics
Preventive healthcare
Healthcare and social care
Contact person (Enter one name per field. Activated personal contact pages will appear automatically): Christina Wedin, Coordinator
Colofonium
Field measurements: No Price type: 1 Division: Division Bioeconomy Preparation: No preparation required Link to order form: Link for order Certification and marking: Not applicable Type of service: Testing / Analysis / Evaluation Instrument: Air flow / Gas flow General area: Gas flow Order information: Order via link below Divison (OLD): Division Bioeconomy Delivery level: Not applicable
christina.wedin@ri.se,
/en/node/9710
PDF for order form.:

Order template (pdf, 218.63 KB)

3. Good health and well-being
9. Industry, innovation and infrastructure
11. Sustainable cities and communities
12. Responsible consumption and production
Metod - Header: Methods Delivery - Header: Delivery
Order
form
Chemical and biological analysis Sekundär områdes navigation:
Health and life science
Pulp and paper
Materials and durability
Tjänstetyp tagg: Provning

Analysis of preservatives (TCMTB, PCMC, OPP, OIT) content in leather

Name of service (page headline, shown in promos – maximum of 70 characters incl. spaces): Determination of leather preservatives (TCMTB, PCMC, OPP, OIT) Lead (include SEO-words and the main benefits for your target groups. Stick to one paragraph, maximum 2-3 sentences):

It is important that the materials on the market are free of hazardous and regulated substances. Chemical analysis is a way to gain control over the products' chemical content.

Purpose/Benefit:

Society and consumers place great demands on companies and their products. The legislation also means that you as an actor must have complete information and control over which chemicals your products contain. It is especially important with products for children and goods that come into contact with the skin, such as clothes and accessories.

We help you interpret chemical legal requirements and restrictions that apply to goods made of textile materials and plastics and that are linked to, for example, REACH and POPs. We suggest which analyzes you need to make based on legal requirements, but also other requirements specifications such as eco-labels or procurement requirements.

Method (what/which methods are used to perform the service):

Determination of leather preservatives (TCMBT, PCMC, OPP, OIT) according to OEKO-TEX

ISO 13365. Leather - Chemical determination of the content of preservatives (TCMTB, PCMC, OPP, OIT) in leather by liquid chromatography

Sample amount 20 grams

Delivery (what does the client get after performed service – e.g. a report, certificate etc.):

Written report in Swedish or English

Delivery time:

The normal delivery time is 10 working days after ordering and received sample material.

Area:
Chemical and biological analysis
Textile
Contact person (Enter one name per field. Activated personal contact pages will appear automatically):
Carina Berglund, Forskare
Elisabeth Olsson, Forsknings- och utvecklingsingenjör
leather
Field measurements: No Price type: 1 Division: Division Materials and Industry Preparation: No preparation required Standards:

OEKO-TEX

ISO 13365

Certification and marking: Not applicable Type of service: Testing / Analysis / Evaluation Instrument: Not applicable General area: Not applicable Order information: Order through the contact persons at the bottom of the page. Divison (OLD): Division Materials and Industry Delivery level: Not applicable
carina.berglund@ri.se,elisabeth.olsson@ri.se
/en/about-rise/operations/mission-governance/policy-documents/privacy-policy
Order
form
Chemical and biological analysis Sekundär områdes navigation:
Metrology
Health and life science
Materials and durability
Tjänstetyp tagg: Provning