Contact person
Francisco Salva Serra
Forskare
Contact Francisco
DOUBLE BARRIER: AI-driven solutions to combat bacterial infections
DOUBLE BARRIER is a Vinnova-funded initiative uniting partners from the US, the UK and Sweden to work together on the development of the concept DOUBLE BARRIER, which aims to integrate AI-driven multi-omics diagnostics and next-generation prevention strategies to combat bacterial infections and antimicrobial resistance (AMR).
Antimicrobial resistance is recognised by the World Health Organization as one of the major threats to global health and sustainable development. Each year, AMR is responsible for over 1 million deaths, and associated with more than 4 million. AMR is constantly raising and thus undermines our capability to treat common infections and challenges the foundations of modern medicine.
The vision is a future where rapid, data-rich, multi-omics-based diagnostics powered by artificial intelligence (AI) enable personalised treatment for infectious diseases, improving patient outcomes. The generated data and AI will also contribute to more effective infection prevention strategies. This flexible, adaptable strategy can integrate diverse omics and clinical data from patients to determine the best treatment for bacterial infections and guide prevention strategies. It will operate in real time, processing each dataset immediately as it is generated.
RISE coordinates the project and provides expertise in genomics, proteomics, clinical microbiology and AI. RISE will lead a pilot study that will take place in London and Washington DC. It will also lead joint funding applications. The project will strenthen the collaboration between the partners: RISE, Sahlgrenska University Hospital, The National Institutes of Health (USA), Veirulence Ltd. (UK) and Imperial College London (UK).
Veirulence Ltd. (UK): company developing virulence factor targeting therapeutics for prevention and treatment of infections.
Imperial College London (UK): provides expertise in metabolomics.
The National Institutes of Health (NIH): provides expertise in –omics data analysis.
Sahlgrenska University Hospital: expertise in clinical microbiology and proteomics.
Summary
Project name
DOUBLE BARRIER
Status
Active
Region
Västra Götaland Region
RISE role in project
Coordinator
Project start
Duration
1 year
Total budget
3,175,142
Partner
Veirulence Ltd. (UK), Imperial College London (UK), National Institutes of Health (USA), Sahlgrenska University Hospital, Culture Collection University of Gothenburg (CCUG)
Funders
Coordinators
RISE Research Institutes of Sweden
Project members
Supports the UN sustainability goals
3. Good health and well-being
12. Responsible consumption and production
16. Peace, justice and strong institutions