Strain-to-scale biotechnology platform

Scaling up a bioprocess often involves multiple sites, suppliers and technology transfers, with each handover increasing the risk of delays and additional costs. RISEs biotechnology platform for upscaling takes you from the laboratory to industrial scale within a single environment.

Virtual tour of the Bioeconomy Arena pilot hall in Örnsköldsvik

The right research and technology infrastructure and the right expertise, all in one place. Step into the pilot hall in Örnsköldsvik and discover how we can help you test, verify and scale up your bio-based solution. →

Strain Development

Successful bioprocesses start with the right microorganism. Our dedicated strain development laboratories combine advanced screening technologies with deep microbiological expertise to identify and optimise production strains for industrial performance.

RISEs capabilities include:

High-throughput screening (HTS)
Adaptive Laboratory Evolution (ALE)
Genetic engineering and metabolic optimisation
Access to extensive microbial diversity collections
Industrial and platform strain banks

Through our large strain library and microbial diversity collection, we can rapidly identify and optimise microorganisms with the characteristics required for robust and cost-effective industrial production.

Fermentation and process scale-up

Once a production strain has been identified or developed, process optimisation and scale-up can proceed seamlessly within the same facility and team.

Our fermentation infrastructure spans the complete development pathway:

Micro-scale: 1 mL to 3 L
Bench scale: 7-50 L
Pilot scale: 100 L, 600 L, 1,000 L and 10,000 L
Batch, fed-batch and continuous cultivation
Food-grade operation
GMM-approved operation
Precision fermentation

This integrated scale-up capability enables rapid translation of laboratory results into industrially relevant process data, ensuring that both microbial performance and process economics are validated under realistic production conditions.

Downstream processing

Commercial success depends on more than fermentation alone. Our downstream processing capabilities allow separation, purification and formulation to be developed alongside the bioprocess, ensuring a scalable end-to-end solution.

Available technologies include:

Centrifugation (disc-stack, tubular and bucket centrifuges)
Filter press systems
Belt drying
Membrane filtration (MF, UF and NF)
Homogenisation
Freeze drying
Chromatography
ATEX-rated solvent handling equipment

By scaling downstream operations in parallel with fermentation, we ensure that the entire manufacturing process is prepared for industrial implementation.

Getting started

Please get in touch with us to explore how the platform can be tailored to your project. In an initial consultation, we will review your strain, process stage and target scale, and outline a development pathway with an estimated timeline and costs.