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NextBioForm's publications

Here you will find research papers from NextBioForm.


Daniel Tristan Osanlóo, Denny Mahlin,  Simon Bjerregaard, Björn Bergenståhl & Anna Millqvist-Fureby. Formulation factors affecting foam properties during vacuum foam-drying International Journal of Pharmaceutics, Volume 652, 2024, 123803

Shuai Bai, Marie Wahlgren, Björn Bergenståhl, Anna Millqvist-Fureby och Emanuel Larsson. Enhancing the stability of probiotics: Freeze-drying and encapsulation. Lund University 2d of February 2024.


Nisha Tyagi, Zandra Gidlöf, Daniel Tristan Osanlóo, Elizabeth S. Collier, Sandeep Kadekar, Lovisa Ringstad, Anna Millqvist Fureby och Stefan Roos. The Impact of Formulation and Freeze Drying on the Properties and Performance of Freeze-Dried Limosilactobacillus reuteri R2LC. Applied Microbiology 2023, 3(4), 1370-1387

Hans Bolinsson, Christopher Söderberg, Fátima Herranz‑Trillo, Marie Wahlgren and Lars Nilsson. Realizing the AF4‑UV‑SAXS on‑line coupling on protein and antibodies using high flux synchrotron radiation at the CoSAXS beamline, MAX IV.  Analytical and Bioanalytical Chemistry, August 12, 2023

Linnea Gustafsson, Mathias Kvick, Carolina Åstrand, Nienke Ponsteen, Nicolai Dorka,Veronika Hegrová, Sara Svanberg, Josef Horák, Ronnie Jansson, My Hedhammar, and Wouter van der Wijngaart. Scalable Production of Monodisperse Bioactive Spider Silk Nanowires. Macromolecular Bioscience, 2023 January 20.

Amanda Västberg, Hans Bolinsson, Mats Leeman, Lars Nilsson, Tommy Nylander, Kushal Sejwal, Ida-Maria Sintorn, Kristina Lidayová, Helen Sjögren, Marie Wahlgren, Ulla Elofsson. Investigating Thermally Induced Aggregation of Somatropin- New Insights Using Orthogonal Techniques. International Journal of Pharmaceutics, Volume 637, 25 April 2023.


Zandra Gidlöf, Betty Lomstein Pedersen, Lars Nilsson, Anita Teleman, Marie Wahlgren, Anna Millqvist-Fureby. Utilising phase diagram to understand barley starch microsphere preparation in an aqueous two-phase systemColloids and Surfaces A: Physicochemical and Engineering Aspects, 658, 130652, 2023.

Shuai Bai Palmkron, Björn Bergenståhl, Sebastian Håkansson, Marie Wahlgren, Anna Millqvist Fureby, Emanuel Larsson. Quantification of structures in freeze-dried materials using X-ray microtomography. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 658, 130726, 2023.

Lingping Zhang, Marie Wahlgren, and Björn Bergenståhl. Oil-Based Delivery Control Release System Targeted to the Later Part of the Gastrointestinal Tract – A Mechanistic Study. Pharmaceutics 14, no. 5: 896. 2022. 

Shuai Bai Palmkron, Linnea Gustavsson, Marie Wahlgren, Björn Bergensthål, Anna Millqvist Fureby. Temperature and Heat Transfer Control During Freeze Drying. Effect of Vial Holders and Influence of Pressure. Pharm Res 39, 2597–2606. 2022. 

Daniel Tristan Osanlóo, Jonas Fransson, Björn Bergenståhl & Anna Millqvist-Fureby. Effects of drying methods on physical properties and morphology of trehalose/mannitol mixtures, Drying Technology, 2022.

Johanna Hjalte, Shakhawath Hossain, Andreas Hugerth, Helen Sjögren, Marie Wahlgren, Per Larsson, Dan Lundberg. Aggregation Behavior of Structurally Similar Therapeutic Peptides Investigated by 1H NMR and All-Atom Molecular Dynamics Simulations. Mol. Pharmaceutics, 19, 3, 904–917. 2022. 

Ingrid Ramm, Mats Leeman, Herje Schagerlöf, Ileana Rodríguez León, Alejandra Castro & Lars Nilsson. Investigation of native and aggregated therapeutic proteins in human plasma with asymmetrical flow field-flow fractionation and mass spectrometry. Anal Bioanal Chem. 2022. 

Adrian Sanchez-Fernandez, Sylvian Prevost, Marie Wahlgren, Deep eutectic solvents for the preservation of concentrated proteins: the case of lysozyme in 1:2 choline chloride : glycerol. Green Chem. 24, 4437-4442. 2022. 

Adrian Sanchez-Fernandez, Johan Larsson, Anna E. Leung, Peter Holmqvist, Orsolya Czakkel, Tommy Nylander, Stefan Ulvenlund, and Marie Wahlgren. Topological Dynamics of Micelles Formed by Geometrically Varied Surfactants. Langmuir  38 (33), 10075-10080. 2022.


Ingrid Ramm, Adrian Sanchez-Fernandez, Jaeyeong Choi, Christian Lang, Jonas Fransson, Herje Schagerlöf, Marie Wahlgren, and Lars Nilsson. "The Impact of Glycerol on an Affibody Conformation and Its Correlation to Chemical Degradation" Pharmaceutics 13, no. 11: 1853. 2021. 

Tuan Phan-Xuan, Ekaterina Bogdanova, Jens Sommertune, Anna Millqvist Fureby, Jonas Fransson, Ann E. Terry, Vitaly Kocherbitov. The role of water in the reversibility of thermal denaturation of lysozyme in solid and liquid states. Biochemistry and Biophysics Reports, Volume 28, 2021,101184.

Johan Larsson, Ashley P. Williams, Marie Wahlgren, Lionel Porcar, Stefan Ulvenlund, Tommy Nylander, Rico F. Tabor, Adrian Sanchez-Fernandez. Shear-induced nanostructural changes in micelles formed by sugar-based surfactants with varied anomeric configuration. Journal of Colloid and Interface Science, Volume 606, Part 1, Pages 328-336. 2022. 

Ekaterina Bogdanova, Anna Millqvist Fureby, Vitaly Kocherbitov. Hydration enthalpies of amorphous sucrose, trehalose and maltodextrins and their relationship with heat capacities. Physical Chemistry Chemical Physics, Issue 26, 2021.

Ali Marefati, Anastasios Pitsiladis, Elin Oscarsson, Niclas Ilestam, Björn Bergenståhl. Encapsulation of Lactobacillus reuteri in W1/O/W2 double emulsions: Formulation, storage and in vitro gastro-intestinal digestion stability. LWT, volume 146, July 2021.

Mats Leeman, Willem M. Albers, Radoslaw Bombera, Johana Kuncova-Kallio, Jussipekka Tuppurainen, Lars Nilsson. Asymmetric flow field-flow fractionation coupled to surface plasmon resonance detection for analysis of therapeutic proteins in blood serum. Analytical and Bioanalytical Chemistry volume 413, 2021.


Mats Leeman, Willem M. Albers, Radoslaw Bombera, Johana Kuncova-Kallio, Jussipekka Tuppurainen, Lars Nilsson. Asymmetric flow field-flow fractionation coupled to surface plasmon resonance detection for analysis of therapeutic proteins in blood serum. Analytical and Bioanalytical Chemistry, volume 413.

Jaeyeong Choi, Catalina Fuentes, Jonas Fransson, Marie Wahlgren, Lars Nilsson. Separation and zeta-potential determination of proteins and their oligomers using electrical asymmetrical flow field-flow fractionation (EAF4)Journal of Chromatography A, volume 1633.

Jaeyeong Choi, Marie Wahlgren, Vilhelm Ek, Ulla Elofsson, Jonas Fransson, Lars Nilsson, Ann Terry, Christopher A. G. Söderberg. Characterization of binding between model protein GA-Z and human serum albumin using asymmetrical flow field-flow fractionation and small angle X-ray scattering. PLoS ONE 2020

Maria Badal Tejedor, Jonas Fransson, Anna Millqvist-Fureby. Freeze-dried cake structural and physical heterogeneity in relation to freeze-drying cycle parameters. International Journal of Pharmaceutics 2020

Tuan Phan-XuanEkaterina Bogdanova, Anna Millqvist Fureby, Jonas Fransson, Ann E. Terry, Vitaly Kocherbitov. Hydration-Induced Structural Changes in the Solid State of Protein: A SAXS/WAXS Study on Lysozyme. Mol. Pharmaceutics 2020

Adrian Sanchez-Fernandez, Carl Diehl, Judith E. Houston, Anna E. Leung, James P. Tellam, Sarah E. Rogers,  Sylvain Prevost,  Stefan Ulvenlund, Helen Sjögren, Marie Wahlgren. An integrative toolbox to unlock the structure and dynamics of protein–surfactant complexes. Nanoscale Advances, 2020.  


Wahlgren M, Axenstrand M, Håkansson Å, Marefati A, Lomstein Pedersen B.  In Vitro Methods to Study Colon Release: State of the Art and An Outlook on New Strategies for Better In-Vitro Biorelevant Release Media. Pharmaceutics. 2019, Feb 22;11(2)


Leeman M, Choi J, Hansson S, Storm MU, Nilsson L. Proteins and antibodies in serum, plasma, and whole blood-size characterization using asymmetrical flow field-flow fractionation. Analytical and Bioanalytical Chemistry 2018, 410, 4867-4873