Pharmaceutical manufacturing without chlorinated solvents

The process step, which has proven problematic, is crucial for controlling the level of contaminants in the final product and the process yield has a significant effect on the amount of chemicals and solvents required in the preceding manufacturing steps.

The project is expected to lead to an increased understanding of how critical impurities are formed in the process and how they can be reduced. Similarly, the project will lead to an increased understanding of the parameters that affect crystallisation and thus enable the development of a robust and efficient process in terms of both yield and quality without, as today, using chlorinated solvents.